We are reporting the neurodevelopmental outcome of the first and only set of Saudi sextuplets (up to date) born at King Khalid University Hospital in Riyadh, Saudi Arabia at the age of 11 years. They were born for a booked mother after induced pregnancy for secondary infertility. Infants were evaluated by Bayley infant Neurodevelopmental Screener (BINS) during the first 24 months of their life and by Revised Gesell Developmental Schedules at age of 30-36 months, for those infants at high risk, and then all were finally evaluated at the age of 11 years by the use of Wechsler Intelligence Scale for Children (WISC). All infants developed Bronchopulmonary dysplasia (BPD), but none of them developed IVH, PVL, blindness, or deafness. All boys showed evidence of spastic diplegia and were at high risk for future neurodevelopmental delay. While all girls had low-moderate risk for future neurodevelopmental delay, none of them showed evidence of cerebral palsy. Their IQ at the age of 11 years ranged from mild mental retardation to normal average intelligence.