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Review Articles On Cytokines

Cytokines are a broad and loose category of small proteins (~5–20 kDa) important in cell signaling. Cytokines are peptides and can't cross the lipid bilayer of cells to enter the cytoplasm. Cytokines are shown to be involved in autocrine, paracrine and endocrine signaling as immunomodulating agents. Cytokines are mainly secreted by the immune cells that act on other cells for coordinated immune reaction. Cytokines binds with high affinity to specific receptors present on the target cells and therefore the cells that show response to the cytokines are either: 1) by same cell that secreted called autocrine, 2) by a neighboring cell called paracrine or 3) by a distant cell reached through the circulation called endocrine. Review articles are the summary of current state of understanding on a specific research topic. They analyse or discuss research previously published by scientist and academicians instead of reporting novel research results. Review article comes within the sort of systematic reviews and literature reviews and are a sort of secondary literature. Systematic reviews determine an objective list of criteria, and find all previously published original research papers that meet the standards. They then compare the results presented in these papers. Literature reviews, against this, provide a summary of what the authors believe are the simplest and most relevant prior publications. The concept of "review article" is breaking away the concept of peer-reviewed literature. It is possible for a review to be peer-reviewed, and it's possible for a review to be non-peer-reviewed.

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