Timely Topics in Clinical Immunology

Tetanus Toxoid

Tetanus vaccine, also called as tetanus toxoid (TT), is an inactive vaccine used to prevent tetanus. During childhood, five doses are suggested, with a sixth given during adolescence. Extra doses every ten years are recommended. After three doses, approximately everyone is originally immune. In those who are not up to date on their tetanus immunization, a inoculation should be given within 48 hours of an injury. In those with high-risk injuries who are not completely immunized, tetanus antitoxin may also be recommended. Making sure pregnant women are up to date on their tetanus immunization can stop neonatal tetanus.

The vaccine is extremely safe, including during pregnancy and in those with HIV/AIDS. Redness and pain at the site of injection occur in between 25% and 85% of people. Fever, feeling tired, and slight muscle pain occurs in less than 10% of people. Severe allergic reactions occur in less than one in 100,000 people.

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