Biology & Medicine Case Reports

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Biology & Medicine Case Reports 44 7897 074717

PROTEIN BIOMARKER JOURNALS

    A bio-marker, or biological marker may be a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated to look at normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention.[1] Biomarkers are utilized in many scientific fields.

                 A  biomarker indicates a change in expression or state of a protein that correlates progression of a disease, or with the susceptibility of the disease to a given treatment. this is often a protein biomarker.
Biomarkers are increasingly viewed as a key adjuvant to drug discovery and development to mitigate the low success rate and high cost the pharmaceutical industry is experiencing. The role of biomarkers spans all aspects of drug discovery and development. Biomarkers could also be used as tools for target discovery, early target assessment, for evaluation of a medicine’s mechanism of action, for dose determination, for prediction of drug effects (efficacy also as adverse reaction), for patient selection/stratification, for therapy monitoring, and for prognostication. While single analytes are the only application of biomarkers, the specified specificity and selectivity may sometimes require the examination of panels of protein and other biomarkers.

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