Integrative Journal of Bone and Cartilage

Integrative Journal of Bone and Cartilage 44 7897 074717

NOVEL BONE MARROW NEWS

Bone drilling (BD) is reconsidered to be a completely unique treatment for pain including vertebral fracture (VCF), vertebral spondylosis, osteoarthritis (OA) and osteonecrosis of the knee and hip, and neuropathic pain. BD is straightforward and harmless. The technique of BD is that the almost like that of bone marrow puncture. BD is conducted under X-ray fluoroscopy and regional anaesthesia . Exact penetration of bone cortex is required for intramedullary decompression, and sufficient aspiration of medullary blood is vital to eliminate intramedullary inflammatory cells (ICs) and inflammatory chemical mediators (ICMs). Onset of the effect is immediate, and therefore the effect lasts several months or a couple of years. On the opposite hand, effectiveness of BD was also shown in neuropathic pain, a representative of complex regional pain syndrome (CRPS.) Neuropathic pain was induced after the nerve root injury, and therefore the bone is usually intact.
                                 A procedure called autologous hematopoietic somatic cell transplantation, commonly referred to as a somatic cell transplant, can often be a crucial treatment option for several patients. Unfortunately, myeloma continues to progress even after a transplant

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