Journal of Clinical Endocrionology Research

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Journal of Clinical Endocrionology Research 44 7897 074717

Endocrine Oncology :

A pancreatic renin-angiotensin system could also be present in humans and should interact with islet cells. Nevertheless, our knowledge of the reninangiotensin system within the human pancreas remains in its infancy, especially within the field of endocrine oncology. Much of our knowledge stems from the study of the pancreas and pancreatic endocrine tumors of rodents. Thus, the direction of future research should be supported in-depth and collaborative efforts between researchers within the various disciplines so as to use the newly acquired knowledge domain to the patient. Pancreatic endocrine tumors are endocrine tumors arising from the cells in the pancreatic islet. They account for about 10% to fifteen of primary pancreatic tumors. The tumors are divided into two groups, functional and non-functional tumors. Functional tumors are those with clinical or biochemical evidence of hormonal production. These tumors are typed consistent with the hormonal syndromes they produce and are called by names like insulinoma, glucagnonoma, gastrinoma, etc. Pancreatic endocrine tumors present a crucial challenge to the clinical management team due to their proteic manifestations, potential lethality and difficulty in predicting the clinical behavior.

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