Microbiology: Current Research

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Microbiology: Current Research 44 7897 074717

Streptomyces Aburaviences Journals

Streptomycetes have established themselves as the most potent group of microorganisms capable of forming a wide variety of antibiotics. The majority of these antibiotic substances are antibacterial in nature and are indispensable for the treatment of bacterial infections of plants and animals including the human beings. On the contrary, antifungal antibiotics effective against fungal disorders are relatively few mainly because of their solubility and toxicity problems. The ever increasing incidence of fungal infections in plants, animals and human being has directed the attention towards the search for actinomycetes producing novel antifungal antibiotics having a broad spectrum of activity and lesser toxicity. Systematic screening of antifungal actinomycetes from Indian soil has been carried out for the production of antibiotics effective against pathogenic fungi. Such screening programs have led to the discovery of a number of antibiotics effective against fungi.

Antibiotic production by a strain is profoundly influenced by the nutritional, physiological and environmental factors prevailing during the growth of the organism. Attainment of high antibiotic production, therefore, requires optimal concentration of the components in the fermentation medium, optimum pH and viscosity.

 

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