Journal of Clinical Respiratory Medicine

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Journal of Clinical Respiratory Medicine 44 7897 074717

Pulmonology Innovations

Pulmonology is a neighborhood of drugs that focuses on the health of the systema respiratorium. s treat everything from asthma to tuberculosis Inflammatory Disease smoking/vaping results in severe disease outcome and mortality amongst tuberculosis patients. SARS-CoV-2 with a membrane spike glycoprotein furin along with its receptor ACE2 and TMPRSS2 protease are increased by smoking/vaping in lung epithelium rendering viral entry and augmented infection. This results in a ‘cytokine storm’ involving excessive production of pro-inflammatory cytokines/chemokines. This review therefore discusses the impact of smoking /vaping on the key inflammatory mechanisms following Covid-19 infection and the possible therapeutic strategies required to medicine in their marketing.

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