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Evidence based assessment of Wild Himalayan Berry (Myrica esculenta Buch) in the management of Polycystic Ovarian Syndrome
8th International Conference on Nutrition, Food Science and Technology
December 09-10, 2019 | Dubai, UAE
Sunita Shailajan
Ramnarain Ruia Autonomous College, India
Keynote : J Food Sci Nutr
Abstract:
Myrica esculenta Buch.-Ham ex D. Don (Myricaceae),
commonly known as Wild Bayberry is locally more
popular as Kaphal. It is a sub-temperate evergreen tree
distributed in the mid-Himalayan regions between 1300
meters and 2100 meters spanning from Pakistan, India,
Nepal and China. Traditionally the fruit is relished by local
communities and is also made into pickles and drinks. It is
highly valued for its medicinal uses. Its bark, flowers, fruits and
leaves are used in Ayurvedic and Unani systems of medicine
against various ailments like menorrhagia, asthma, anaemia,
tumors, bronchitis, menstrual disorders etc. Myrica esculenta is
reported for its hepatoprotective, antibacterial, antifungal, antihelminthic
and anti-inflammatory activities. It is an important
ingredient of Ayurvedic formulations like Chawyanprash,
Katphaladi churna, Khadiradi gutika and Pushyanuga churna
etc.
The plant is reported to be rich in various bioactive
phytochemicals like gallic acid, ellagic acid, catechin, myricetin,
stigmasterol, beta sitosterol, lupeol, quercetin etc. The fruit
is also rich in amino acids, ascorbic acid, caffeic acid, transcinnamic
acid etc. Current study evaluates the potential use
of this wild Himalayan berry in the management of Polycystic
Ovarian Syndrome (PCOS). PCOS is a reproductive disorder
with multiple etiological factors severely affecting the fertility
of the woman. PCOS also leads to obesity and diabetes. The
current work envisages the use of this berry as a nutraceutical
supplement during the therapeutic treatment of PCOS. This
work evaluates the quality parameters of the Himalayan berry
using phytochemical fingerprints developed using HPTLC.
The quantitation of bioactive marker; gallic acid has been
achieved with a validated HPTLC technique. The paper reports
experimental evidence in support of efficacy of the berry
in mitigating symptoms associated with PCOS using the rat
model. The bioavailability of bioactives from the berry is also
demonstrated using pharmacokinetic studies in rats.
Biography:
Sunita Shailajan (Ramnarain Ruia Autonomous College, Mumbai, India, currently working as a principal investigator in DST - SERB project, Govt. of India) Area of specialization: Quality evaluation of traditional formulations using HPTLC and HPLC techniques, pharmacological (toxicity and efficacy), and pharmacokinetics. Patents-02 Member HPTLC association (HPTLC ASSOCIATION International Association for the Advancement of High- Performance Thin Layer Chromatography), Switzerland.
E-mail: sunitashailajan@gmail.com
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