Journal of Cell Science and Mutations

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Journal of Cell Science and Mutations 44 7897 074717

Spermatogonial Stem Cells Peer Review Journals

Spermatogenesis originates from spermatogonial stem cells (SSCs). The Development of spermatogonial transplantation technique in 1994 provided the primary practical assay to characterize SSCs. The neurogliacyte line-derived neurotrophic issue was known as an SSC self-renewal issue. This discovery is not solely provided a clue to grasping SSC self-renewing mechanisms however additionally created it is attainable to derive germline stem (GS) cell cultures in 2003. In vitro culture of GS cells incontestable their potential pluripotency and their utility in germline modification. However, in vivo SSC analyses have challenged the standard thought of SSC self-renewal and have discovered their relationship with the microenvironment.

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