Journal of Parasitic Diseases: Diagnosis and Therapy

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Journal of Parasitic Diseases: Diagnosis and Therapy 44 7897 074717

MALARIA ONLINE JOURNAL

Malaria is caused by mosquito  that affects humans and other animals.
Malaria is caused by single-celled microorganisms of the Plasmodium group. The disease is most ordinarily spread by an infected female Anopheles mosquito. The sting introduces the parasites from the mosquito's saliva into an individual's blood. The parasites visit the liver where they mature and reproduce. Five species of Plasmodium can infect and be spread by humans. Most deaths are caused by P. falciparum, whereas P. vivax, P. ovale, and P. malariae generally cause a milder sort of malaria. The species P. knowlesi rarely causes disease in humans. Malaria is usually diagnosed by the microscopic examination of blood using blood films, or with antigen-based rapid diagnostic tests.  Methods that use the polymerase chain reaction to detect the parasite's DNA are developed, but aren't widely utilized in areas where malaria is common thanks to their cost and complexity.
The risk of disease are often reduced by preventing mosquito bites through the utilization of mosquito nets and bug repellents, or with mosquito control measures like spraying insecticides and draining stagnant water As of 2020, there's one vaccine which has been shown to scale back the danger of malaria by about 40% in children in Africa. Efforts to develop simpler vaccines are ongoing. The recommended treatment for malaria may be a combination of antimalarial medications that has an artemisinin. The second medication could also be either mefloquine, lumefantrine, or sulfadoxine/pyrimethamine. Quinine along side doxycycline could also be used if an artemisinin isn't available. it's recommended that in areas where the disease is common, malaria is confirmed if possible before treatment is started thanks to concerns of accelerating drug resistance. Resistance among the parasites has developed to many antimalarial medications; for instance , chloroquine-resistant P. falciparum has spread to most malarial areas, and resistance to artemisinin has become a drag in some parts of Southeast Asia .

 

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