Journal of Public Health and Nutrition

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Journal of Public Health and Nutrition 44 7897 074717

Induced Pluripotent Stem Cells Top Open Access Journals

Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell. The iPSC technology was pioneered by Shinya Yamanaka’s lab in Kyoto, Japan, who showed in 2006 that the introduction of four specific genes (named Myc, Oct3/4, Sox2, and Klf4) encoding transcription factors could convert somatic cells into pluripotent stem cells. He was awarded the 2012 Nobel Prize along with Sir John Gurdon "for the discovery that mature cells can be reprogrammed to become pluripotent.

Pluripotent stem cells hold promise in the field of regenerative medicine.

 

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