Journal of Cancer Clinical Research

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Journal of Cancer Clinical Research 44 7897 074717

Hereditary Colorectal Review Articles

Hereditary nonpolyposis colorectal cancer is characterized by  the autosomal dominant genetic condition this is combined  by a high risk of colon cancer just as well as other cancers along with  endometrial cancer ,ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, skin and brain. There are a number of different inherited conditions this have a significant risk of colon cancer. It is predicted that 15-50% of colorectal cancers are familial. A single gene has a combination of genes or a combination of genetic and environmental factors may cause familial colorectal cancer. Typically these families that   includes one or two members with a history of colorectal cancer or precancerous polyps. Inherited colorectal cancers are combined with a genetic mutation in a cancer susceptibility gene. 

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