Journal of Chemical Technology and Applications

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Journal of Chemical Technology and Applications 44 7897 074717

Gel Permeation Chromatography

Gel permeation chromatography (GPC) is a kind of size exclusion chromatography (SEC), that separates analytes on the basis of size, usually in organic solvents. The technique is commonly used for the analysis of polymers. As a method, SEC was 1st developed in 1955 by lathe and Ruthven.The term gel permeation chromatography is copied back to J.C. Moore of the Dow Chemical Company who investigated the technique in 1964 and therefore the proprietary column technology was licenced to Waters Corporation, who later commercialised this technology in 1964. GPC systems and consumables are also available from variety of makers. it's usually necessary to separate polymers, each to research them moreover on purify the required product.When characterizing polymers, it's vital to consider the dispersity (Đ) moreover the molecular weight. he size average molecular weight (Mz), or the viscosity molecular weight (Mv). GPC permits for the determination of Đ moreover as Mv and based on alternative information, the Mn, Mw, and Mz is determined.

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