Hematology and Blood Disorders

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Endomyocardial Fibrosis

Endomyocardial fibrosis (EMF) is a rare sickness in North America but common in the tropical and subtropical regions of the developing world. It is characterized by fibrosis of the left ventricular and right ventricular endocardium which cause restrictive cardiomyopathy. In common areas of Africa, endomyocardial fibrosis is an important cause of heart failure accounting for up to 20% of the cases. Currently, the exact etiology and pathogenesis of the disease remain unknown. However, its pathology resembles conditions such as eosinophilic cardiomyopathy and hypereosinophilic syndrome. As a result, EMF is sometimes measured part of a single disease method that also includes Loffler endocarditis (eosinophilic endomyocardial fibrosis).

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