Case Reports in Surgery and Invasive Procedures

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Dna Sequencing

Every organism’s DNA consists of a unique sequence of nucleotides. Determining the sequence can help scientists compare DNA between organisms, which can help show how the organisms are related. Though DNA sequencing used to take years, it can now be done in hours.  Now, certain companies will sequence your entire genome for less than $1,000. Sanger sequencing continues to be useful for determining the sequences of relatively long stretches of DNA, especially at low volumes. However, it can become expensive and laborious when a large number of molecules need to be sequenced quickly. Ironically, though the traditional dye-terminator method is useful when the DNA molecule is longer, high-throughput methods have become more widely used, especially when entire genomes need to be sequenced.

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