Journal of Chemical Technology and Applications

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Biotransformation

Biotransformation is that the chemical modification (or modifications) made by an organism on a compound . If this modification ends in mineral compounds like CO2, NH4+, or H2O, the biotransformation is named mineralisation.

Biotransformation means chemical alteration of chemicals like nutrients, amino acids, toxins, and medicines within the body. it's also needed to render non-polar compounds polar in order that they're not reabsorbed in renal tubules and are excreted. Biotransformation of xenobiotics can dominate toxicokinetics and therefore the metabolites may reach higher concentrations in organisms than their parent compounds. Recently its application is seen as an efficient, cost effective, and simply applicable approach for the valorization of agricultural wastes with potentials of enhancing existing bioactive components and synthesis of latest compounds.

Biotransformation is significant to survival because it transforms absorbed nutrients (food, oxygen, etc.) into substances required for normal body functions. for a few pharmaceuticals, it's a metabolite that's therapeutic and not the absorbed drug.

For example, phenoxybenzamine, a drug given to alleviate hypertension caused by pheochromocytoma, a sort of tumor, is biotransformed into a metabolite, which is that the active .

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