Journal of Gastroenterology and Digestive Diseases

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Journal of Gastroenterology and Digestive Diseases 44 7897 074717

Anticancer Drug Development

Due to the tremendous increase in our appreciation of the cancer process and cause, development of drugs to selectively interfere with and prevent tumour growth has now entered a new and exciting era of the target oriented approach. Drugs are now being established against specific proteins involved in cancer cell growth that have been discovered over the last 10 years or so. These differences cover all areas of cancer biology, from cell signalling pathways to tumour hypoxia and from angiogenesis to cell death pathways. It therefore follows that to develop drugs that interfere with these complex paths, a comprehensive knowledge of the cancer process is required by today's cancer researcher. This book gives a very broad overview of the whole of the anticancer drug development procedure today, from chemical synthesis to the clinic.

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