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Editorial - Journal of Molecular Oncology Research (2020) Volume 4, Issue 4
Expansion of Prostate Cancer at Single Cell Level
Mutational changes makes the cells in the prostate gland undergo uncontrollable cell divisions, due to which the gland increases size, this leads to the benign prostate hyperplasia (BPH). Every organ in the human body consists of few common cells, similarly prostate gland also comprises of few cell types like luminal and basal epithelial cells, neuroendocrine cells, fibroblasts, lymphocytes, macrophage and endothelial cells. Each cell has its own function based on the gene expression. Sometimes the cells also perform functions of other neighbouring cells via intercellular communication, this specific functions and intercellular communication makes any tissue stabilised and balanced that is tissue homeostasis, which is lacking in the cancer tissues.
Author(s): Eva Jagelska