Timely Topics in Clinical Immunology

Timely Topics in Clinical Immunology 44 7897 074717

Scholarly Peer-review Journals On Nanotechnology In HIV

Research of healthcare efforts in Nanotechnology deal with fighting and diagnosing the Human immunodeficiency virus (HIV) which causes AIDS (Acquired Immune Deficiency Syndrome). Nanotechnology offers a important opportunity to improve and combine various profiles of pharmacology of anti-retroviral drugs, with suitable drug administration and potentially better patient adherence for HIV therapy.

This can also be a benefit for a huge part or portion which results in developing countries through nanotechnology process, where the so called ‘big three’ diseases (HIV/AIDS, malaria and tuberculosis) are responsible for millions of deaths.

For example, the antiviral efficacy of classic cocktail therapy is significantly restricted by the distinct profiles of pharmacokinetic for therapeutic partner that lead to inconsistent in vivo bio-distribution, which is said to be traditional. In one recent research study, scientists developed a new cocktail-like drug delivery vehicle using biodegradable polymeric nanoparticles encapsulating non-nucleoside reverse transcriptase inhibitor, surface-conjugated with HIV-1 fusion inhibitor, and aiming to achieve improved antiviral activity, increased cellular uptake, and prolonged circulation of blood time.

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