Journal of Pharmacology and Therapeutic Research

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Journal of Pharmacology and Therapeutic Research 44 7897 074717

Role Of Thyroid Hormones Research Articles

The thyroid hormones act on nearly every cell within the body. They act to extend the basal rate, affect protein synthesis, help regulate so longum growth (synergy with growth hormone) and neural maturation, and increase the body's sensitivity to catecholamines by permissiveness. Thyroid hormones are two hormones produced and released by the thyroid, namely triiodothyronine (T3) and thyroxin (T4). They are tyrosine-based hormones that are primarily liable for regulation of metabolism. T3 and T4 are partially composed of iodine. A deficiency of iodine results in decreased production of T3 and T4 enlarges the thyroid tissue and can cause the disease referred to as simple goitre. Having too much T3 in the bloodstream is referred to as thyrotoxicosis. This condition often results from over activity within the thyroid, or hyperthyroidism. Hyperthyroidism occurs in conditions such as Graves’ disease, inflammation of the thyroid or a benign tumor. Signs of thyrotoxicosis include weight loss, increased appetite, palpitations, irregular menstrual cycle, tiredness, irritability, and hair thinning. Hyperthyroidism can also occur when supplements with T3 are ingested. The impact factor of a journal is evaluated by dividing the amount of current year citations to the source items published therein journal during the previous two years.

 

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