Virology Research Journal

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Physical Organic Chemistry

Physical chemistry – the study of the interplay between structure and reactivity in organic molecules – underpins chemistry, and that we cannot imagine chemistry as a topic without knowledge of mechanism and reactivity. It’s sometimes thought that the golden age of ‘physical organic chemistry’ was within the 20th century, when systematic information about mechanism first burst onto the scene. Definitely the influence of initial knowledge of device of fundamental aliphatic replacement reactions, among others, was enormous, but our knowledge of reactivity and mechanism has continued to progress and deepen enormously ever since and this has been reflected during a number of Nobel Prizes in Chemistry. In a neighbourhood of particular interest to me, the transformation of radical chemistry from being an almost impenetrable area to at least one which will be usefully harnessed even in synthetic applications. This alteration is relatively recent and has been principally hooked in to the accurate determination of kinetics of radical reactions.

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