Integrative Journal of Bone and Cartilage

Integrative Journal of Bone and Cartilage 44 7897 074717

Novel Bone Marrow Journals

Bone drilling (BD) is reconsidered to be a completely unique treatment for pain including vertebral fracture (VCF), vertebral spondylosis, osteoarthritis (OA) and osteonecrosis of the knee and hip, and neuropathic pain. BD is straightforward and harmless. The technique of BD is that the almost like that of bone marrow puncture. BD is conducted under X-ray fluoroscopy and regional anaesthesia . Exact penetration of bone cortex is required for intramedullary decompression, and sufficient aspiration of medullary blood is vital to eliminate intramedullary inflammatory cells (ICs) and inflammatory chemical mediators (ICMs). Onset of the effect is immediate, and therefore the effect lasts several months or a couple of years. However, precise of the underlying mechanisms of BD remains unclear.

The effectiveness of BD was also shown in neuropathic pain, a representative of complex regional pain syndrome (CRPS.) Neuropathic pain was induced after the nerve root injury, and therefore the bone is usually intact. However, BD alleviates a foot ache that's produced thereafter. This fact may indicate that subsequent medullary inflammation occurs and bone tissue is involved in CRPS. Therefore, a particular change within the bone is induced by CRPS. the very fact suggests a hypothesis that a self-facilitating mechanism of pain is provided independently within bone marrow. Sumihisa Aida, Pain Relief by Bone Drilling and Osseous Pain Sensitization

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