Allied Journal of Medical Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Allied Journal of Medical Research 44 7897 074717

News Of Lipidomics

Human milk provides the infant with the essential nutritive and non-nutritive factors required for health, growth and development. The human milk lipidome is complex, but comprises predominantly triacylglycerides. Historically, the carboxylic acid profile of the whole human milk lipidome has been investigated, and lots of relationships are identified between infant health and fatty acids. Most of those fatty acids are, however, delivered to the infant as triacylglycerides. Using liquid chromatography-ion mobility-mass spectrometry, the target of this study was to characterise the triacylglyceride profile of human milk and elucidate relationships between the triacylglyceride profile and infant outcomes during a cohort of 10 exclusively breastfeeding woman-infant dyads. 205 triacylglycerides were identified, including 98 previously not reported in human milk. The dose of specific triacylglycerides differed in reference to infant health, like dodecanoic acid containing TAGs, which were delivered in significantly higher dose to healthy infants compared to unwell infants.

The lipids in human milk (HM) are vital to the infant, not only because the main source of energy for infant growth, but in their role in immunological interactions and serving as structural components of the infant neural and retinal systems. The HM lipidome is complex, with lipids strategically packaged as milk fat globules (MFG). The MFG encapsulates triacylglycerides (TAGs) inside the core, making up 98–99% of the entire HM lipidome, while the encompassing MFG membrane consists of other more polar lipids like cholesterol and phospholipids. the entire lipids are the foremost variable macronutrient of HM, with sample concentrations varying anywhere between approximately 2 and 100 g/L, increasing throughout a feed, changing throughout the day, and typically increasing throughout lactation

High Impact List of Articles
Conference Proceedings

Relevant Topics in Medical Sciences

Get the App