Allied Journal of Medical Research

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Allied Journal of Medical Research 44 7897 074717

Lipidomics And Its Importance

Lipidomics may be a newly emerged discipline that studies cellular lipids on an outsized scale supported analytical chemistry principles and technological tools, particularly mass spectrometry. Recently, techniques have greatly advanced and novel applications of lipidomics within the biomedical sciences have emerged. This review provides a timely update on these aspects. After briefly introducing the lipidomics discipline, we compare mass spectrometry-based techniques for analysis of lipids and summarize very recent applications of lipidomics in health and disease. Finally, we discuss the status of the sector , future directions, and advantages and limitations of the sector .
Lipids are crucial components of cellular membranes and lipid particles like lipoproteins. Lipids play many essential roles in cellular functions, including cellular barriers, membrane matrices, signaling, and energy depots. Cellular lipids are highly complex; that's , there are tens to many thousands molecular species at concentrations starting from amol to nmol/mg protein . Cellular lipids also are highly dynamic; that's , they're changing constantly with physiological, pathological, and environmental conditions. Lipids are classified into alittle number of classes and subclasses. Lipidomics (see Glossary) emerged in 2003 and has greatly advanced in recent years, largely thanks to the event of mass spectrometry (MS) .

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