Journal of Histology and Cell Biology

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Immunohistochemistry

Immunohistochemistry is the most typical application of immune staining. It consist of the process about the selectively identifying antigens in the cells of a tissue section through exploiting the principle of antibodies binding specifically to antigens in biological tissues. Immunohistochemistry takes its name taken away the roots "immuno"  in reference to antibodies are used in the procedure and "histo", it means tissue compares to immunocytochemistry. Albert Coons conceptualized and first implemented the procedure in 1941. Immunohistochemical staining is generally used in the diagnosis of abnormal cells like as those are found in cancerous tumors. Specific molecular markers are distinctive of particular cellular events like as proliferation or cell death.

Relevant Topics in Genetics & Molecular Biology