Journal of Pregnancy and Neonatal Medicine

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Follicle Stimulating Hormone

Follicle stimulating hormone is one among the gonadotrophic hormones, the opposite being luteinising hormone. Both are released by the pituitary into the bloodstream. Follicle stimulating hormone is one among the hormones essential to pubertal development and therefore the function of women’s ovaries and men’s testes. In women, this hormone stimulates the expansion of ovarian follicles within the ovary before the discharge of an egg from one follicle at ovulation. It also increases oestradiol production. In men, follicle stimulating hormone acts on the Sertoli cells of the testes to stimulate sperm production (spermatogenesis).

The production and release of follicle stimulating hormone is regulated by the amount of variety of circulating hormones released by the ovaries and testes. this technique is named the hypothalamic–pituitary–gonadal axis. Gonadotrophin-releasing hormone is released from the hypothalamus and binds to receptors within the anterior pituitary gland gland to stimulate both the synthesis and release of follicle stimulating hormone and luteinising hormone. The released follicle stimulating hormone is carried within the bloodstream where it binds to receptors within the testes and ovaries. Using this mechanism follicle stimulating hormone, along side luteinising hormone, can control the functions of the testes and ovaries.

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