Journal of Diabetology

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Articles On Diabetes Mellitus

Diabetes mellitus is a metabolic disorder characterized by impaired action, secretion of insulin or both, resulting in hyperglycemia. Although the definition, the pathophysiological basis and much of management of DM is glucocentric, it is a true metabolic disorder, and a number of metabolic disturbances have been characterized. In addition to experiencing well-known complications associated with DM such as premature cardiovascular disease, renal disease, retinopathy and neuropathy, about one-third of people with DM have severe periodontal disease. Attenuated immunity, which occurs as a result of hyperglycemia and a variety of host factors associated with DM may be the pathophysiological basis for the increased prevalence and severity of periodontal disease.

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