Archives in Food and Nutrition

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +1 (629)348-3199

Opinion Article - Archives in Food and Nutrition (2024) Volume 7, Issue 1

Silent battleground: Unveiling the secrets of vitamin b12 deficiency and strategies for prevention.

Toribio Soley *

Department of Nutrition, Federal University of Santa Catarina (UFSC). Santa Catarina, Brazil.

*Corresponding Author:
Toribio Soley
Department of Nutrition, Federal University of Santa Catarina (UFSC). Santa Catarina, Brazil.
E-mail: dd>

Received: 03-Feb-2024, Manuscript No. AAAFN-24-126692; Editor assigned: 05-Feb-2024, PreQC No AAAFN-24-126692 (PQ) Reviewed:17-Feb-2024, QC No. AAAFN-24-126692Revised:19-Feb-2024, Manuscript No. AAAFN-24-126692 (R); Published:24-Feb-2024, DOI:10.35841/aaafn-7.1.191

Citation: Soley T. Silent battleground: Unveiling the secrets of vitamin b12 deficiency and strategies for prevention. Arch Food Nutr. 2024;7(1):191

Visit for more related articles at Archives in Food and Nutrition


Introduction In the intricate dance of nutrition and health, the significance of vitamin B12 often goes unnoticed until its absence reverberates through the body, unraveling a silent battleground within. Vitamin B12 deficiency, while subtle in its early stages, can have profound consequences on one's well-being. As we delve into the secrets of this deficiency, this article aims to shed light on the silent struggles faced by many and unveil strategies for its prevention [1].

Vitamin B12, a water-soluble vitamin, plays a crucial role in various physiological processes. It is essential for the formation of red blood cells, neurological function, and the synthesis of DNA. Found predominantly in animal products such as meat, fish, and dairy, vitamin B12 is a nutrient that often poses a challenge for individuals following vegetarian or vegan diets [2].

The body's ability to absorb vitamin B12 also relies on the intricate interplay of stomach acids, enzymes, and intrinsic factor – a protein crucial for B12 absorption. Any disruption in this delicate balance can pave the way for vitamin B12 deficiency, setting the stage for a cascade of health issues [3].

One of the unique aspects of vitamin B12 deficiency is its ability to quietly manifest over time, often eluding immediate detection. The symptoms, ranging from fatigue and weakness to neurological complications, can be subtle and easily attributed to other factors. The silent struggles within the body may continue unabated until more severe consequences emerge, including anemia, nerve damage, and cognitive impairments [4].

Particularly concerning is the insidious nature of vitamin B12 deficiency in older adults, where symptoms may be dismissed as a natural part of aging. Unraveling the secrets of this deficiency requires heightened awareness and proactive measures to address potential risk factors [5].

Understanding the risk factors and causes of vitamin B12 deficiency is key to its prevention. Vegetarians and vegans face a higher risk due to the limited dietary sources of B12. Additionally, individuals with certain medical conditions such as pernicious anemia, atrophic gastritis, or celiac disease may experience impaired B12 absorption [6].

Medications, including proton pump inhibitors and metformin, can also interfere with B12 absorption. Unraveling the secrets of vitamin B12 deficiency involves recognizing these risk factors and addressing them proactively to mitigate the chances of deficiency [7].

Preventing vitamin B12 deficiency requires a multifaceted approach, encompassing dietary choices, lifestyle adjustments, and, in some cases, supplementation. Here are key strategies for unveiling the secrets of vitamin B12 deficiency and preventing its silent progression [8].

Ensure a well-balanced diet that includes B12-rich foods. For non-vegetarians, this includes fish, meat, and dairy products. Vegetarians and vegans should consider fortified foods or supplements. In cases where dietary intake is insufficient or absorption is compromised, B12 supplements can be an effective preventive measure. Consultation with a healthcare professional is crucial to determine the appropriate dosage [9].

Dispel the silence around vitamin B12 deficiency by raising awareness about its importance and potential risks. Education empowers individuals to make informed decisions about their dietary choices and seek timely medical advice [10].


By unraveling the secrets of vitamin B12 deficiency, we empower individuals to take charge of their health and well-being. The silent battleground need not be a losing one; instead, it can be transformed into a proactive arena where preventive measures and early intervention prevail. Let us bring the silent struggles of vitamin B12 deficiency into the spotlight, fostering a culture of awareness and proactive health management. In doing so, we pave the way for a future where the secrets of this deficiency are unveiled and its consequences are averted, ensuring optimal health and vitality for all.


  1. Roberts SB, Rosenberg I. Nutrition and aging: Changes in the regulation of energy metabolism with aging. Physiol Rev. 2006;86(2):651-67.
  2. Indexed atGoogle ScholarCross Ref

  3. Soultoukis GA, Partridge L. Dietary protein, metabolism, and aging. Annu Rev Biochem. 2016;85:5-34.
  4. Indexed atGoogle ScholarCross Ref

  5. Luís C, Maduro AT, Pereira P, et al. Nutritional senolytics and senomorphics: Implications to immune cells metabolism and aging–from theory to practice. Front Nutr. 2022;9:958563.
  6. Indexed atGoogle ScholarCross Ref

  7. Russell RM. The aging process as a modifier of metabolism. Am J Clin Nutr. 2000;72(2):529S-32S.
  8. Indexed atGoogle ScholarCross Ref

  9. Slawik M, Vidal-Puig AJ. Lipotoxicity, overnutrition and energy metabolism in aging. Ageing Res Rev. 2006;5(2):144-64.
  10. Indexed atGoogle ScholarCross Ref

  11. Yaku K, Okabe K, Nakagawa T. NAD metabolism: Implications in aging and longevity. Ageing Res Rev. 2018;47:1-7.
  12. Indexed atGoogle ScholarCross Ref

  13. Das JK, Salam RA, Thornburg KL, et al. Nutrition in adolescents: physiology, metabolism, and nutritional needs. Ann N Y Acad Sci. 2017;1393(1):21-33.
  14. Indexed atGoogle ScholarCross Ref

  15. Le Couteur DG, Solon-Biet SM, Cogger VC, et al. Branched chain amino acids, aging and age-related health. Ageing Res Rev. 2020;64:101198.
  16. Indexed atGoogle ScholarCross Ref

  17. Amarya S, Singh K, Sabharwal M. Changes during aging and their association with malnutrition. J Clin Gerontol Geriatr. 2015;6(3):78-84.
  18. Indexed atGoogle ScholarCross Ref

  19. Franceschi C, Garagnani P, Parini P, et al. Inflammaging: a new immune–metabolic viewpoint for age-related diseases. Nat Rev Endocrinol. 2018;14(10):576-90.
  20. Indexed atGoogle ScholarCross Ref

Get the App