Journal of Clinical and Experimental Toxicology

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Short Communication - Journal of Clinical and Experimental Toxicology (2020) Volume 4, Issue 3

synthesis of new structures of imidazolium salts

As result of the strongly basic character of heterocyclic carbenes 1,they react with Broenstedt acids and have consequently been used as selective deprotonation reagents. The 2H-imidazolium salts formed by this method are accessible by other routes, alkylation of 2H-imidazoles,cyclization reactions or from the thiones and nitric acid,and may be used as precursors in the synthesis of 1 through deprotonation.
So our current research efforts also continue to focus on design and synthesis of new structures of imidazolium salts. Therefore, Owing the strongly basic character of heterocyclic carbenes reacted with methyl phenyl disulfide to give the corresponding adduct 2which afford a new synthetic route for 2,3-dihydro-imidazole-2-thione. While the reaction of 1 with bis-methane sulfone was carried out at RT to give the salt 4.  
 
 
Author(s): Eyad Mallah

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