Research Article - Journal of Pharmacology and Therapeutic Research (2018) Volume 2, Issue 2
Survival of the patients after the first episode of AMI according to the risk factors
Introduction: The term “risk factors” describe those characteristics that are found in healthy persons that are connected in an independent way with the occurrence of the associated cardiovascular disease. This term includes the lifestyle, biochemical and physiological modified characteristics, and also the personal unmodified characteristics such as: age, gender, and family history in the occurrence of cardiovascular disease in the early age (male<55 year’s old, female<65 years old).
Aim: Evaluation of predictive ability of risk factors of patients at the moment of the hospitalization in long-term prognosis of the patients with a new myocardial infarct, during the progression of 3 years of the patients after a new episode of myocardial infarct in the Elbasan region.
Methodology: It is a cohort study for a period of 3 years, to value the prognostic abilities of the clinical characteristics of the patients in the moment of hospitalization in undesired results in long-term like the new occurrence of the infarct. To assess the effect of risk factors of cardiovascular disease in the occurrence or not in an another episode of AMI, we used the analysis curve of survival Kaplan Meier in the SPSS 16. A p<0.05 is considered significant.
Results: From 65 patients involved in the study, at the end of the study period, 16 of them had had an interest events (death/reinfarct) that is a significant way lower than its non-repeating (p<0.05). Change in the level of survival of individuals with AMI according to the presence or not the high blood pressure, according to the family history, use or not tobacco for the AMI is not statistically significant (Log Rank p>0.05). Changes in the level of survival of individuals according to the cholesterol level normal or high, presence or not of the diabetes has changes in the statistics (Log Rank p<0.05).
Conclusion: Knowledge of the risk factors that are also a prognosis factor of the patient performance with AMI helps in defining patients that needs to undergo a more specific check-up to avoid these undesired results. The reason that patients has been smokers, have, hypercholesterolemia history are at a higher risk to have a reserved prognosis of the disease (recurrence of myocardial infarct or death). Knowledge of this group would help in composition of personalized pursuance of the patients trying to reduce chances of the repeating of AMI and elimination in the time the recurrence of AMI.Author(s): Brunilda Elez