Archives of General Internal Medicine

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Case Report - Archives of General Internal Medicine (2022) Volume 6, Issue 5

Erythromelalgia- An atypical manifestation of reactive thrombocytosis in Dengue fever.

Dengue, also referred to as break bone fever or dandy fever is a febrile viral illness commonly found in tropical and sub-tropical climates worldwide, with a higher prevalence in urban and semi urban areas. Dermatologic manifestations of dengue infection can be erythema, morbilliform eruptions, and hemorrhagic lesions. Erythromelalgia is characterised by intense redness, burning pain and increased local temperature of the affected extremities that may occur episodically or continuously. Erythromelalgia may be primarily idiopathic or may be caused by underlying disorders like nerve damage due to injuries, autoimmune diseases like lupus vasculitis, multiple sclerosis and infection like viral fever. Reactive thrombocytosis (RT) refers to abnormally high platelet count in absence of chronic myeloproliferative disease occurring in response to any pre-existing inflammatory, infectious or hemorrhagic condition. The common infections that are associated with RT are skin/soft tissue, urinary tract infection, pneumonia followed by gastrointestinal infection. We present a case of an elderly male with dengue fever induced reactive thrombocytosis causing erythromelalgia.

Author(s): Nandini Sanjeev Bandil, Divit Shah, Shubhi Gupta*, Shubhangi Setia, Sourya Acharya, Samarth Shukla

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