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Research Article - Journal of Child and Adolescent Health (2025) Volume 9, Issue 1
Differences and factors associated with dyslipidemias in American adolescents of Hispanic and Asian Indian descent.
Introduction: Hispanics, South Asians, and African American have demonstrated disproportionately high manifestation of abnormal lipid profiles in obese adolescents and those with a family history of Cardiovascular (CV) diseases. Results of lipid screening during routine preventive care pediatric visits in Hispanic and Asian Indian adolescents which have not been routinely reported were analyzed.
Methods: Demographic and clinical data, including age, gender, health insurance coverage, and anthropometric parameters at time of lipid screening were utilized. Blood sugar and lipid profile measurements, including total cholesterol, low-density lipoprotein, triglyceride, and high-density lipoprotein were categorized as acceptable, borderline, high, or as combined dyslipidemia by stages of adolescence of early, middle, and late and sex-age based percentile for body mass index category of overweight and obese adolescents. Univariate analysis using chi-square and analysis of variance identified dyslipidemia categories between Asian Indians and Hispanic adolescents based on age stage.
Results: Overall, 428 adolescents, 244 Asian Indians and 184 Hispanics included 41.4% in early, 45.8% in middle, and 12.8% in late age stages were studied. A significantly higher proportion of Hispanics of any age stage had abnormal BMI. Average blood lipid concentrations of TC, LDL-C, and HDL-C were higher in Asian Indians in early and middle age stages. Combined data of adolescents in middle and late age stages identified a higher rate of multifactorial dyslipidemia in Asian Indians.
Conclusion: Routine lipid screening should be implemented as unidentified overweight/obese adolescents predicted all types of dyslipidemias, irrespective of ethnicity, gender, and age.
Author(s):Naveen Mehrotra, Nayan Mehrotra, Anna Petrova