Commentary - Journal of Clinical Ophthalmology (2023) Volume 7, Issue 6

Commentary on recent advancements in impression cytology.

Impression Cytology (IC) is a pivotal development to the field of ophthalmology, introduced in 1977 as a method for obtaining cells from the superficial ocular surface [1]. Its role has evolved and expanded, with recent advances in the diagnostic landscape of both ocular and systemic diseases potentially reshaping its clinical applicability [2]. Initially developed for identifying squamous metaplasia in ocular cells, IC's versatility has been underscored by its role in diagnosing ocular pathologies such as dry eye disease and ocular surface diseases. The primary advantage of IC lies in its non-invasive nature, minimal discomfort to patients, and its capability to allow repetitive sampling. Recent scientific developments in high throughput bioinformatic analyses (transcriptomic and proteomics) highlight the potential for IC to have a larger and more impactful role in the diagnosis of systemic conditions and scientific discovery

Author(s): Andre Galenchik Chan, Lauren Langman, Konstantinos Tourmouzis, ,Basil Rigas,Dean Khwaja, Robert Honkanen

Abstract Full Text PDF