Allied Journal of Medical Research

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Allied Journal of Medical Research 44 7897 074717

Target Based Drug Designing

Pharmacophores correspond to ordinary chemical features connected to an affinity for a exact receptor. They explain how structurally diverses ligands can bind to a common receptor site. promising fragments correspond to a combination of chemical features associated to a class of chemicals. These two notions are very close but one (pharmacophore) is based on the definition of common characteristic associated to a class of derivatives and the second (emerging fragment) is based on the association of chemical datasets (normally two datasets).Polypharmacological properties are associated to all molecules interacting with biological processes. The issue is to control these properties by a specific orientation towards therapeutic targets

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