Journal of Trauma and Critical Care

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Journal of Trauma and Critical Care 44 7897 074717

Post Traumatic Stress Disorder Peer Review Journal

Trauma in childhood may be a grave psychosocial, medical, and public policy problem that has serious consequences for its victims and for society. Chronic interpersonal violence in children is common worldwide. Developmental traumatology, the systemic investigation of the psychiatric and psychobiological effects of chronic overwhelming stress on the developing child, provides a framework and principles when empirically examining the neurobiological effects of pediatric trauma. Despite the widespread prevalence of childhood trauma, less is understood about trauma's biological effects in children as compared to adults big trauma histories; and even less is understood about how these paediatric mechanisms underlie trauma's short-term and long-term medical and psychological state consequences. This text focuses totally on the peer-reviewed literature on the neurobiological sequelae of childhood trauma in children and adults with histories of childhood trauma. We also review relevant studies of animal models of stress to assist us better understand the psychobiological effects of trauma during development. Next, we review the neurobiology of trauma, its clinical applications and therefore the biomarkers which will provide important tools for clinicians and researchers, both as predictors of posttraumatic stress symptoms and as useful tools to watch treatment response. Finally, we provide suggestions for future researchers.

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