Biology & Medicine Case Reports

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Cell Line

Cell lines are established proliferating cells in culture derived from various organ and sources utilized in basic research and early stage drug development studies. the selection of appropriate cell line depends on the organism of study, the disease investigated, and therefore the tissue or organ of interest. Human, mouse, and rat cells are similar in protein and disease expression, which makes them accepted options for all-purpose studies. HEK-293 (Human Embryonic Kidney) cells are ubiquitously utilized in preliminary protein expression studies due to their easy growth and transfection. Transfected cell lines also are available for the analysis of receptors, G proteins, and ion channels. Hamster, monkey, and bug cell lines are samples of sources of ovary, lung, and parasites for the investigation of protein expression or organ function. Most cell lines are shipped frozen with or without media and equipped for transfection, so it's imperative to settle on compatible transfection and cell line products.

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