Asian Journal of Biomedical and Pharmaceutical Sciences

Asian Journal of Biomedical and Pharmaceutical Sciences 44 7897 074717

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Which contracts with consequence of numerous pharmacological agents studied on altered animal species, which aims out the therapeutic agent appropriate for human use, study of toxicity of the drugs and the study the mechanism and site of action of drugs, the discovery of new drugs or to study the actions of existing drugs which is of preclinical and clinical where preclinical undergoes two ways intact animal study and isolated organ study while coming with clinical phase with 1,2,3,4 Laboratory animals – breaded and handled in laboratory Mice Rat Guinea pig Rabbits RAT , Advantages and characteristics are small in size, drug to be tested required in small quantity ,vomiting centre is absent – oral administration can be done, pancreas are diffused therefore difficult to produce panereactomy, stomach, fundus and pyloric parts are pure covering between them, Intestinal acid secretion is incessant.

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