Journal of Infectious Diseases and Medical Microbiology

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Journal of Infectious Diseases and Medical Microbiology 44 7897 074717

Antimicrobial Agent Innovations

Due to the public health threat of antibiotic resistance has gained attention at the highest political levels globally, and recommendations on how to respond are being considered for execution. Among the recommended responses being explored for their feasibility is the introduction of economic incentives to sponsor investigate and develop new antibiotics. There is broad agreement that public investment should stimulate innovation and be linked to policies promoting sustainable and equitable access to antibiotics. The clinical pipeline remains inadequate to tackle the challenge of growing emergence and spread of antimicrobial resistance. Eight new antibacterial agents have been approved since 1 July 2017, but overall, they have limited clinical benefits. An agent was considered innovative if there was an absence of known cross-resistance to existing antibiotics.

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