Chlorhexidine and bioglass can preserve the resin-dentine bonding
2nd International Conference on Dental Health and Oral Hygiene
September 05-06, 2019 | London, UK
Ali A Alharbi
Alkharj Armed Forces Hospital, Saudi Arabia
Posters & Accepted Abstracts : J Clin Dentistry Oral Health
Despite all the improvements resin based dental
adhesive materials have gone through, leakage in
the resin-dentine interface is still a major limitation of
resin based dental restorative materials. Dentine matrix
metalloproteinases have been associated with this leakage
through their involvement in the proteolytic degradation
of the resin-dentine hybrid layer. The inhibitory effect of
chlorhexidine on this enzymatic activity is well established.
Bioactive glass materials can also reduce the resin-dentine
interface leakage through remineralisation of the dentine.
In this study RelyXTM Unicem AplicapTM was modified by incorporating chlorhexidine and Bioglass 45S5 into the cement composition. One hundred and fifty dentine specimens were obtained from human permanent single rooted teeth and restored with the test cements. The test cements push-out bond strength was measured and statistically analysed after ageing the specimens in artificial saliva for one week and after nine months. The matrix metalloproteinases activity was also quantified after each storage period. The study results showed that incorporating chlorhexidine and Bioglass 45S5 jointly or separately into the composition of RelyXTM Unicem AplicapTM did reduce MMP-2 activity after the short- and long-term storage. It was also shown by the results of this work that incorporating chlorhexidine and Bioglass 45S5 jointly, and chlorhexidine separately into the composition of the cement also reduced MMP-9 activity after short- and long-term storage.
Statistical analyses of the test results has shown that incorporating chlorhexidine and Bioglass 45S5 into the RelyXTM Unicem Aplicap TM cement composition significantly preserves the push-out bond strength after up to nine months of storage (p=0.02).