+441518081136Biomaterials as targeted tool for medical applications
Joint Event on International Conference on Organic and Inorganic Chemistry & 8th World Congress on Green Chemistry and Technology
February 18-19, 2019 | Paris, France
Amany A Mostafa
National Research Centre, Egypt
Posters & Accepted Abstracts : J Ind Environ Chem
Abstract:
Over the past decades, biomaterials play an important role in the field of medicine and health care. The use of synthetic biomaterials has extensive progress due to chronic diseases, malfunction, traumatic accendients and surgical reconstruction. Many research works have been focused on biomaterials in the field of tissue engineering, drug delivery besides imaging as a diagnostic tool. Targeted delivery of drug incorporated nanoparticles as well as 3D scaffolds will enhance the efficacy of the anticancer or other organ-targeted drugs but also reduce the unwanted toxicity of the drug. Our team developed some promising nanobiomaterials and nanohybrids for the improvement of physical, mechanical and cell-biomaterial interactions beside controlling the targetting drug release. Different techniques have been used to prepare nanobiomaterials that help in improving the human life. New formula incorporated these nanoparticles with an antiinflammatory drug is used for the nonsurgical treatment of preapical lesion arisng trauma or bacterial infection as an innovative tool. Kinetic approach has been used to asses the in vitro bioactivity of differnt nanocomposites formulae used in bone regeneration. Other work aimed to the use of cationic bPEI capped AuNPs for intracellular siRNA delivery that targeted c-Myc gene in human hepatocellular carcinoma cells. Material for imaging such as quatum dots stabilized with magnetic nanopaticles or carbon dots are also benifiial. A multidisciplenary team has been involved in these work activities. Herein, I will present and discuss different laboratoy’s research advancement for medical applications.
Biography:
E-mail:
amani.mostafa@gmail.comPDF HTML