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Page 29
Note:
Biotechnology Congress 2018 & Emerging Materials 2018
Biomedical Research
|
ISSN: 0976-1683
|
Volume 29
S e p t e m b e r 0 6 - 0 7 , 2 0 1 8 | B a n g k o k , T h a i l a n d
allied
academies
Joint Event on
EMERGING MATERIALS AND NANOTECHNOLOGY
BIOTECHNOLOGY
&
Annual Congress on
Global Congress on
José Vidal Gancedo et al., Biomed Res 2018, Volume 29 | DOI: 10.4066/biomedicalresearch-C4-010
RADICAL DENDRIMERS
José Vidal Gancedo, Vega Lloveras Monserrat
and
Luiz Pinto
Instituto de Ciencia de Materiales de Barcelona – CSIC, Spain
O
ur interest is focused on the study of molecular materials based on
radicaldendrimersandtheirmagneticand/orelectricpropertiesaswell
as their possible biomedical applications. Dendrimers are a very special
class of hyperbranched macromolecules, which are synthesized step-by-
step to ensure a good monodispersed. The three-dimensional structure
of these molecules proceeds from the central core with exponentially
increasing number of repeated units and terminal groups. The term
radical dendrimers have been used in the case of highly functionalized
dendrimers with organic radicals. There are only few examples of fully
functionalized dendrimers with organic radicals to study the magnetic
behavior. Here we present a series of dendrimers built with phosphorus
as branching points and with nitroxyl radicals as end groups. Molecules
with many unpaired electrons, which possess high-spin ground state and
stability at room temperature, are particularly challenging and promising
targets. The interaction between pendant stable radicals at the exterior
of the dendritic surface and their dynamic behavior can be studied
using Electron Paramagnetic Resonance (EPR) spectroscopy. This is
important to understand the magnetic properties of these functionalized
dendrimers. We describe several generations of phosphorus dendrimers
with stable radicals’ end groups as well as the crystal.
José Vidal Gancedo is tenured Scientist at the Mate-
rials Science Institute of Barcelona, ICMAB-CSIC and
at the Networking Research Center on Bioengineering,
Biomaterials and Nanomedicine, CIBER-BBN, Barce-
lona, Spain. He is Scientist in charge of the ICMAB
Electron Paramagnetic Resonance Laboratory and
Secretary of The Spanish Electron Paramagnetic Res-
onance Group, GERPE. He co-authored more than 140
journal articles and book chapters and four patents
and his H-factor is 32. His research interest focuses
on molecular functional materials based in organic
radicals, molecular nanoscience, and nanomedicine.
j.vidal@icmab.esBIOGRAPHY