Microbiology: Current Research

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Commentary - Microbiology: Current Research (2022) Volume 6, Issue 5

The human microbiome in health and disease

Joshua Olovo*

Department of Microbiology, University of Nigeria Nsukka, Enugu State, Nigeria

*Corresponding Author:
Joshua Olovo
Department of Microbiology
University of Nigeria Nsukka
Enugu State, Nigeria
E-mail: Joshua.Olovo@unn.edu.ng

Received: 29-Aug-2022, Manuscript No. AAMCR-22-77355; Editor assigned: 01-Sep-2022, Pre QC No. AAMCR-22-77355(PQ); Reviewed: 15-Sep-2022, QC No. AAMCR-22-77355; Revised: 20-Sep-2022, Manuscript No. AAMCR -22-77355(R); Published: 28-Sep-2022, DOI: 10.35841/aamcr-6.5.124

Citation: Olovo J. The human microbiome in health and disease. J Micro Curr Res. 2022;6(5):124

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Despite the impact of the human microbiome on health, an appreciation of microbial ecology is yet to be translated into mainstream medical training and practice. The human microbiota plays a role in the development of the immune system, in the development and function of the mind, in digestion, and in host defense, and we guess that a lot more functions are yet to be found. We contend here that without formal openness to microbiology and ecology fields that investigate the organizations, associations and elements between individuals from populaces of microorganisms indispensably significant connections between the human microbiome and wellbeing will be disregarded. This instructive shortage affects patient consideration and biomedical examination, and we give models from momentum research featuring the impact of the microbiome on human wellbeing. We infer that officially integrating microbiology and ecology into the premedical educational programs is priceless to the preparation of future wellbeing experts and basic to the advancement of novel therapeutics and treatment practices.


Premedical curricula, Microbiology, Human microbiome, Ecology.


The influential American microbiologist D. H. Bergey was a promoter for adding bacteriology as a fundamental part of the general preparation of science understudies and those trying to acquire clinical preparation as soon as 1915. After 100 years, in 2015, obviously numerous organ frameworks and physiological capabilities in the human body are tweaked by little particles got from the microbiota and that the microbiome is a vital determinant of human wellbeing [1]. Additionally, the human body can be seen as a complicated and complex biological system, and human wellbeing can be deciphered to a limited extent as a result of the environment benefits that are conveyed by its inhabitant microbiota. The elements of microbial networks related with these environments can be unequivocally tweaked by neighborhood associations with our resistant, endocrine and sensory systems. Every natural surroundings gives an exceptional specialty space to the development and endurance of native and attacking microorganisms, and movements of the human body from a 'solid' non-unhealthy state to a sick condition are much of the time joined by significant changes in microbial development and local area piece. We in this manner contend here that proper consideration of microbial science and environment is fundamental in the premedical science educational plan due to the complicated and joined connections that we share with our microbial accomplices: archaea, microorganisms, infections and microeukaryotes like growths [2].

In this audit, we feature the job of environmental and microorganism have communications in human wellbeing, and we frame what openness to microbial nature in premedical educational plans can mean for clinical practice. The more extensive subject of how the human biological system cooperates with natural environments, albeit similarly significant, isn't shrouded in that frame of mind as it has been talked about somewhere else. We likewise give brief models that show the significant expected job of the human stomach microbiome under four different patient settings: (i) the organization of anti-infection agents, (ii) the presence of metabolic problems, (iii) the advancement of disease and (iv) the pharmacokinetics of medications inside the patient. For each of these four examples, we highlight the potential integration of practices in the clinic with discoveries in basic microbiome research and ecology [3].

The human microbiome is described by an organization of microorganism and organisms have collaborations that is normally impervious to humble variances in diet, chemicals, safe reaction and intrusions by pathogenic and non-pathogenic organisms. In any case, solid irritations, for example, treatment with anti-toxins can prompt significant changes in microbial local area structure from which the microbiome some of the time never totally recuperates and can affect human wellbeing [4]. The development of information and innovation in environment, microbial science, organic chemistry, immunology as well as different fields makes coordination of these disciplines with medication a characteristic following stage. In the four areas later, we have decided to zero in additional itemized conversation on the clinical significance of the stomach microbiota, however comparable standards can be applied to other human body locales where organism microorganism and organism have associations can affect wellbeing and sickness. We also acknowledge that the microbiota of the gut can potentially modulate mental health, immunity and many other clinically relevant issues in human medicine [5].


Our resident microbiota play important roles in homeostatic physiology and a large group of constant sickness conditions. Practically these communications are interceded through energy and metabolite trade among human and microbial cells, and through the adjustment of human and microbial quality articulation. Doctors need admittance to explicit, quantitative measurements that can impartially be utilized to survey their patients' wellbeing state (for example urinalyses; platelet counts and serum science; groupings of key compounds and chemicals in tissues and liquids). Doctors likewise may unequivocally profit from breaking down their patients' microbiome for biomarkers that can be utilized to identify microbe-associated health conditions.


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