Archives of Industrial Biotechnology

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Perspective - Archives of Industrial Biotechnology (2023) Volume 7, Issue 4

Nutrigenomics and mutation breeding: Developing crops for personalized nutrition.

Andrew Henslee *

Department of Chemical and Biomolecular Engineering, Ohio State University

*Corresponding Author:
Andrew Henslee
Department of Chemical and Biomolecular Engineering, Ohio State University, Columbus, Ohio, USA

Received: 10-Jul-2023, Manuscript No. AAAIB-23-112117; Editor assigned: 12-Jul-2023, PreQC No. AAAIB-23-112117 (PQ); Reviewed:26-Jul-2023, QC No. AAAIB-23-112117; Revised:28-Jul-2023, Manuscript No. AAAIB-23-112117 (R); Published:04-Aug-2023, DOI:10.35841/ aaaib -7.4.158

Citation: Henslee A. Nutrigenomics and mutation breeding: Developing crops for personalized nutrition. 2023;7(4):158

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In an era where health and well-being are at the forefront of public consciousness, the intersection of genetics, nutrition, and agriculture has given rise to a revolutionary concept: personalized nutrition. With the advent of advanced techniques like nutrigenomics and mutation breeding, scientists are now exploring innovative ways to develop crops that cater to individual dietary needs, ultimately enhancing human health and nutrition. This article delves into the dynamic field of nutrigenomics, the potent tool of mutation breeding, and their collaborative potential in creating crops tailored for personalized nutrition. Nutrigenomics, a portmanteau of "Nutrition" and "Genomics," is a cutting-edge discipline that investigates how individual genetic makeup influences responses to nutrients and diet. At the core of nutrigenomics lies the understanding that our genetic variations can influence how our bodies absorb, metabolize, and utilize nutrients. These genetic variations can also impact our susceptibility to certain health conditions, making it crucial to tailor dietary recommendations according to individual genetic profiles. By analyzing an individual's genetic markers, scientists can identify specific dietary requirements and make personalized recommendations to optimize health outcomes. Nutrigenomics empowers individuals to make informed dietary choices that align with their genetic predispositions, leading to more effective and sustainable improvements in health and well-being [1].

Mutation breeding is a classical technique that harnesses the power of genetic variation to develop improved crop varieties. This method involves inducing mutations in plant DNA through exposure to mutagenic agents, such as radiation or chemicals. These induced mutations generate genetic diversity, and through careful selection and screening, crop varieties with desired traits can be identified and propagated. The beauty of mutation breeding lies in its ability to enhance beneficial traits, such as yield, nutritional content, and disease resistance, without introducing foreign genetic material. This process is akin to nature's own evolutionary mechanisms, but accelerated under controlled conditions to produce desired outcomes within a relatively short span of time [2].

The convergence of nutrigenomics and mutation breeding opens up a realm of possibilities for personalized nutrition through crop development. By identifying genes responsible for nutrient accumulation, taste, and other vital traits, nutrigenomics can guide the selection of plants with inherent potential to address specific dietary needs. Imagine a scenario where nutrigenomic insights reveal that an individual requires higher levels of a particular nutrient due to their genetic makeup. This information could then guide the mutation breeding process to develop crops with elevated nutrient levels tailored to that individual's needs. Such personalized crops could provide a tangible solution to the global challenge of malnutrition and deficiencies [3].

Numerous case studies highlight the promise of combining nutrigenomics and mutation breeding. One such example is the development of high-iron beans through mutation breeding. Iron deficiency is a prevalent global health issue, particularly in regions where staple diets lack this essential mineral. By using mutagenic agents to induce genetic changes, scientists successfully created bean varieties with significantly higher iron content, addressing a critical nutritional gap. Similarly, in rice, scientists have utilized both nutrigenomics and mutation breeding to enhance the grain's nutritional profile. By identifying genes linked to nutrient absorption and utilization, researchers could target these genes for mutation breeding to develop rice varieties enriched with essential vitamins and minerals [4].

As with any scientific advancement, the synergy between nutrigenomics and mutation breeding presents challenges and ethical considerations. Safety assessments, environmental impact, and public acceptance are critical factors that researchers must carefully navigate. Ensuring that personalized crops are safe for consumption, environmentally sustainable, and ethically sound is essential to the responsible development of this technology. The combined power of nutrigenomics and mutation breeding holds the potential to revolutionize agriculture and nutrition. As scientific understanding deepens and technologies evolve, personalized nutrition through crop development could become a reality on a larger scale. However, achieving this goal requires interdisciplinary collaboration between geneticists, nutritionists, agronomists, and policy makers [5].


In conclusion, the convergence of nutrigenomics and mutation breeding represents a remarkable stride toward personalized nutrition. This innovative approach has the capacity to address complex nutritional challenges and promote healthier lives through tailored dietary choices. By marrying genetic insights with crop development, scientists are not only sowing the seeds of future crops but also nurturing a healthier and more sustainable world for generations to come. As research progresses, the potential of this collaborative effort promises to bring us closer to the realization of personalized nutrition through the bounty of the earth's harvest.



  1. Dyo YM, Purton S. The algal chloroplast as a synthetic biology platform for production of therapeutic proteins. Microbiol.2018;164(2):113-21.
  2. Indexed at, Google Scholar, Cross Ref

  3. Economou C, Wannathong T, Szaub J, et al. A simple, low-cost method for chloroplast transformation of the green alga Chlamydomonas reinhardtii. Methods Mol Biol. 2014;1132:401-11.
  4. Indexed at, Google Scholar, Cross Ref

  5. Giraldo JP, Landry MP, Faltermeier SM, et al. Plant nanobionics approach to augment photosynthesis and biochemical sensing. Nat Mater. 2014;13(4):400-8.
  6. Indexed at, Google Scholar, Cross Ref

  7. Liu J, Chang J, Jiang Y, et al. Fast and efficient CRISPR/Cas9 genome editing in vivo enabled by bioreducible lipid and messenger RNA nanoparticles. Adv Mater. 2019;31(33):1902575.
  8. Indexed at, Google Scholar, Cross Ref

  9. Merchant SS, Allen MD, Kropat J, et al. Between a rock and a hard place: trace element nutrition in Chlamydomonas. Biochim Biophys Acta. 2006;1763(7):578-94.
  10. Indexed at, Google Scholar, Cross Ref

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