Archives of Industrial Biotechnology

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Commentary - Archives of Industrial Biotechnology (2023) Volume 7, Issue 2

Bioproduction of Sustainable Chemicals: A Promising Pathway towards a Greener Future

Vijay Kumar Sharma*

Department of Biotechnology & Bioinformatics, Jaylee University of Information Technology (JUIT), Waknaghat, India

Corresponding Author:
Vijay Kumar Sharma
Department of Biotechnology & Bioinformatics
Jaylee University of Information Technology (JUIT)
Waknaghat, India.
Email id:

Received: 20-Mar-2023, Manuscript No. AAAIB-23-106932; Editor assigned: 22-Mar-2023, PreQC No. AAAIB-23-106932(PQ); Reviewed: 05-Apr-2023, QC No. AAAIB-23-106932; Revised: 07-Apr-2023, Manuscript No. AAAIB-23-106932(R); Published: 14-Apr-2023, DOI:10.35841/aaaib-7.2.136

Citation: Sharma VK. Bio production of Sustainable Chemicals: A Promising Pathway towards a Greener Future. J Arch Ind Biot. 2023;7(2):136

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In recent years, the demand for sustainable chemicals has been steadily increasing as industries strive to reduce their environmental impact and transition towards more sustainable practices. Bio production, the process of utilizing living organisms or their enzymes to produce chemicals, offers a promising pathway to achieve this goal. By harnessing the power of biotechnology, researchers and industries are now able to produce a wide range of sustainable chemicals, including biofuels, bioplastics, and specialty chemicals, in a more environmentally friendly and economically viable manner. In this article, we will explore the concept of bio production, its advantages, and its potential to revolutionize the chemical industry towards a greener future.

What is bio production?

Bio production, also known as bio-based production or bio manufacturing, refers to the use of living organisms, such as bacteria, yeast, algae, or enzymes derived from them, to produce chemicals or chemical compounds. It harnesses the natural metabolic pathways and enzymatic capabilities of these organisms to convert renewable feedstocks, such as agricultural residues, lignocellulosic biomass, or waste streams, into valuable chemical products. Bio production can be performed through fermentation, enzymatic reactions, or a combination of both.

Advantages of bio production

Sustainability: One of the major advantages of bio production is its inherent sustainability. By utilizing renewable feedstocks, such as plant biomass or waste materials, it reduces the reliance on fossil resources and helps mitigate the carbon footprint associated with traditional chemical production methods. Bio production also offers the potential to utilize carbon dioxide as a feedstock, thus contributing to carbon capture and utilization efforts.

Reduced energy consumption: Bio production processes often operate under mild conditions, such as ambient temperatures and pressures, which require less energy compared to traditional chemical synthesis methods. Additionally, bio production can achieve high yields and selectivity, minimizing waste generation and reducing energyintensive purification steps [1].

Diversification of feedstocks: Bio production offers the flexibility to use a wide range of feedstocks, including lignocellulosic biomass, agricultural residues, and waste streams. This diversification reduces dependence on limited resources and promotes the utilization of waste materials, thereby contributing to the circular economy and waste reduction.

Product diversity: Bio production enables the production of a wide range of chemicals, including biofuels, bioplastics, specialty chemicals, and pharmaceutical intermediates. This versatility allows for the development of sustainable alternatives to conventional chemicals, meeting the diverse needs of various industries.

Biodegradability and environmental safety: Many chemicals produced through bio production are inherently biodegradable and pose minimal risk to the environment compared to their synthetic counterparts. This aspect is crucial in industries where chemical residues may enter ecosystems and impact biodiversity and water quality [2].

Applications of bio production

Biofuels: Bio production has made significant contributions to the production of biofuels, such as bioethanol, biodiesel, and biogas. Microorganisms like yeast and bacteria can ferment sugars derived from biomass to produce bioethanol, which can be used as a renewable fuel additive or a standalone fuel. Similarly, lipids from algae or other microbial sources can be converted into biodiesel through enzymatic reactions or transesterification processes.

Bioplastics: Bio production plays a vital role in the production of biodegradable and renewable bioplastics. Through fermentation processes, microorganisms can produce biopolymers like polylactic acid (PLA) and polyhydroxyalkanoates (PHA), which serve as sustainable alternatives to conventional petroleum-based plastics.

Specialty chemicals: Bio production enables the synthesis of various specialty chemicals, such as enzymes, organic acids, amino acids, and vitamins. Microorganisms can be genetically engineered to produce these chemicals at high yields and purity, providing sustainable alternatives to traditional chemical synthesis methods.

Pharmaceutical intermediates: Bio production offers a costeffective and sustainable approach to produce pharmaceutical intermediates and Active Pharmaceutical Ingredients (APIs). Microorganisms can be engineered to produce complex molecules through metabolic engineering and fermentation processes, reducing reliance on chemical synthesis routes that may involve hazardous or non-renewable starting materials [3].

Challenges and future perspectives

While bio production holds great promise for sustainable chemical production, several challenges need to be addressed for its widespread adoption:

Bio production processes require careful optimization to achieve high yields, productivity, and cost-effectiveness. This involves balancing metabolic pathways, optimizing culture conditions, and developing robust fermentation and downstream processing strategies.

The development of efficient and genetically stable microorganisms or enzymes for specific chemical production remains a challenge. Genetic engineering techniques and synthetic biology approaches are being employed to improve the performance and productivity of bio production strains [4].

Moving from lab-scale to industrial-scale bio production involves significant challenges, such as maintaining consistent productivity, addressing contamination risks, and optimizing process economics. Robust scale-up strategies and techno-economic analysis are crucial for successful commercialization.

Bio produced chemicals may require regulatory approvals and face public perception challenges, particularly regarding Genetically Modified Organisms (GMOs). Clear regulations and effective communication about the safety and benefits of bio production are essential to foster public acceptance [5].


Bio production offers a sustainable and environmentally friendly pathway for the production of a wide range of chemicals. By harnessing the power of living organisms, bio production reduces reliance on fossil resources, minimizes energy consumption, and diversifies feedstock sources. The applications of bio production span across biofuels, bioplastics, specialty chemicals, and pharmaceutical intermediates, contributing to the development of a greener and more sustainable chemical industry. Overcoming challenges related to process optimization, strain development, scale-up, and regulatory aspects will further enhance the adoption of bio production. With ongoing advancements in biotechnology and increased industry focus on sustainability, bio production is poised to play a significant role in shaping a more sustainable future.


  1. Weger L, Abánades A, Butler T. Methane cracking as a bridge technology to the hydrogen economy. Int J Hydrog Energy. 2017;42(1):720-31.
  2. Google Scholar

  3. Pellis A, Acero EH, Ferrario V, et al. The closure of the cycle: enzymatic synthesis and functionalization of bio-based polyesters. Trends Biotechnol. 2016;34(4):316-28.
  4. Indexed at, Google Scholar, Cross Ref

  5. Herrero Acero E, Ribitsch D, Steinkellner G, et al. Enzymatic surface hydrolysis of PET: effect of structural diversity on kinetic properties of cutinases from Thermobifida. Macromolecules. 2011;44(12):4632-40.
  6. Google Scholar

  7. Charfi A, Thongmak N, Benyahia B, et al. A modelling approach to study the fouling of an anaerobic membrane bioreactor for industrial wastewater treatment. Bioresour Technol. 2017;245:207-15
  8. Indexed at, Google Scholar, Cross Ref

  9. Koschuh W, Thang VH, Krasteva S, et al. Flux and retention behaviour of nanofiltration and fine ultrafiltration membranes in filtrating juice from a green biorefinery: a membrane screening. J Membr Sci. 2005;261(1-2):121-8.
  10. Google Scholar

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