Insights in Nutrition and Metabolism

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +1 (202) 780-3397

Brief Report - Insights in Nutrition and Metabolism (2023) Volume 7, Issue 4

A brief analysis on gestational diabetes mellitus.


David Lois*

Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA

*Corresponding Author:
David Lois
Department of Preventive Medicine
University of Southern California Keck School of Medicine
Los Angeles, California, USA

Received:27-Jun-2023,Manuscript No. AAINM-23-107298; Editor assigned: 30-Jun-2023, PreQC No. AAINM-23-107298(PQ); Reviewed:14-Jul-2023, QC No. AAINM-23-107298; Revised:19-Jul-2023, Manuscript No. AAINM-23-107298(R); Published:25-Jul-2023, DOI: 10.35841/aainm-7.4.155

Citation: Lois D. A brief analysis on gestational diabetes mellitus. Insights Nutr Metab. 2023;7(4):155

Visit for more related articles at Insights in Nutrition and Metabolism


Gestational Diabetes Mellitus (GDM) is a temporary form of diabetes that occurs during pregnancy. It affects a significant number of pregnant women worldwide and can have implications for both the mother and the developing fetus. This article aims to provide a comprehensive overview of gestational diabetes, including its causes, symptoms, diagnosis, and management strategies. By understanding this condition, expectant mothers, healthcare professionals, and support networks can work together to ensure optimal outcomes for both mother and baby[1].

Causes of gestational diabetes

Gestational diabetes develops when the body's insulin sensitivity is impaired during pregnancy. The exact causes are not fully understood, but several risk factors contribute to its development. These risk factors include maternal obesity, a family history of diabetes, advanced maternal age, polycystic ovary syndrome (PCOS), and a history of gestational diabetes in previous pregnancies. Hormonal changes during pregnancy, such as increased levels of certain hormones produced by the placenta, can also interfere with insulin function.

Symptoms and complications

Gestational diabetes often does not cause noticeable symptoms, which is why regular screening tests are crucial for early detection. However, some women may experience symptoms such as increased thirst, frequent urination, fatigue, and recurrent infections. If left unmanaged, gestational diabetes can lead to various complications for both the mother and the baby. The mother may be at risk of developing preeclampsia, high blood pressure, and type-2 diabetes later in life. The baby may experience macrosomia (large birth weight), birth injuries, hypoglycemia (low blood sugar) after birth, and an increased risk of developing obesity and type 2 diabetes later in life[2].

Diagnosis and screening

Diagnosing gestational diabetes involves screening pregnant women between 24 and 28 weeks of gestation, although high-risk individuals may be tested earlier. The standard screening test is the oral glucose tolerance test (OGTT). During this test, the woman drinks a glucose solution, and blood samples are taken at specific intervals to measure blood glucose levels. If the test results exceed specific thresholds, a diagnosis of gestational diabetes is made. Early detection is crucial to implement appropriate management strategies promptly[3].

Management and treatment

The management of gestational diabetes primarily focuses on maintaining blood glucose levels within a target range to minimize complications. Treatment plans typically involve dietary modifications, regular physical activity, and, in some cases, insulin therapy or oral medication.

Dietary modifications: Women with gestational diabetes are advised to follow a balanced, individualized meal plan, which includes consuming adequate calories and nutrients while controlling carbohydrate intake. This involves spreading meals throughout the day, including high-fiber foods, and avoiding sugary and processed foods.

Regular physical activity: Engaging in moderate-intensity exercise, such as walking or swimming, helps improve insulin sensitivity and manage blood glucose levels. Expectant mothers should consult their healthcare providers to develop an appropriate exercise plan tailored to their needs.

Glucose monitoring: Regular self-monitoring of blood glucose levels using a glucose meter is essential to track and adjust the management plan accordingly. Healthcare providers may recommend specific target ranges for fasting and postprandial (after meal) blood glucose levels.

Insulin and medication: If blood glucose levels remain uncontrolled despite lifestyle modifications, insulin therapy or oral medication may be prescribed. Insulin is safe for use during pregnancy and can effectively manage high blood sugar levels[4].

Postpartum care and long-term considerations

After delivery, gestational diabetes typically resolves, and blood sugar levels return to normal. However, both the mother and the child remain at a higher risk of developing type-2 diabetes in the future. Therefore, postpartum care is essential for continued monitoring and preventive measures.

Postpartum glucose testing: Women with gestational diabetes should undergo a follow-up glucose tolerance test six to twelve weeks after delivery to confirm the resolution of diabetes. This test also helps identify individuals at risk of developing type-2 diabetes.

Lifestyle modifications: Maintaining a healthy lifestyle with regular physical activity and a balanced diet is crucial for preventing or delaying the onset of type 2 diabetes. Breastfeeding has also been shown to reduce the risk of both the mother and the baby developing diabetes.

Long-term monitoring: Women with a history of gestational diabetes should undergo regular diabetes screenings, typically every one to three years. It is important to maintain a healthy weight, manage blood pressure, and control other cardiovascular risk factors[5].


Gestational diabetes poses temporary challenges for expectant mothers and their unborn babies. However, with appropriate management and support, the risks associated with this condition can be minimized. Regular screenings, early diagnosis, lifestyle modifications, and personalized treatment plans are key to maintaining optimal health for both mother and child. By understanding the causes, symptoms, diagnosis, and management strategies of gestational diabetes, healthcare providers and support networks can work together to ensure the best possible outcomes for pregnant women and their families.


  1. Jenum AK, Mørkrid K, Sletner L, et al.Impact of ethnicity on gestational diabetes identified with the WHO and the modified International Association of Diabetes and Pregnancy Study Groups criteria: A population-based cohort study.Eur J Endocrinol. 2012;166(2):317-24.
  2. Indexed at, Google Scholar, Cross Ref

  3. Mission JF, Ohno MS, Cheng YW, et al.Gestational diabetes screening with the new IADPSG guidelines: a cost-effectiveness analysis.Am J Obstet Gynecol. 2012;207(4):326-1.
  4. Indexed at, Google Scholar, Cross Ref

  5. Morikawa M, Yamada T, Yamada T, et al.Change in the number of patients after the adoption of IADPSG criteria for hyperglycemia during pregnancy in Japanese women.Diabetes Res Clin Pract. 2010;90(3):339-42.
  6. Indexed at, Google ScholarCross Ref

  7. Crowther CA, Hiller JE, Moss JR, et al.Effect of treatment of gestational diabetes mellitus on pregnancy outcomes.N Engl J Med. 2005;352(24):2477-86.
  8. Indexed at, Google Scholar, Cross Ref

  9. Dabelea D, Pettitt DJ.Intrauterine diabetic environment confers risks for type-2 diabetes mellitus and obesity in the offspring, in addition to genetic susceptibility.J Pediatr Endocrinol Metab. 2001;14(8):1085-92.
  10. Indexed at, Google Scholar, Cross Ref

Get the App