Biomedical Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research Article - Biomedical Research (2019) Volume 30, Issue 6

EBUS-TBNA Biopsy for Pulmonary Sarcoidosis Diagnosis.

Objective: To evaluate the diagnostic efficacy and safety of EBUS-TBNA for biopsy for pulmonary
sarcoidosis.
Methods: Seventy eight patients with suspected sarcoidosis were retrospectively included in the present
work. The included patients were received either mediastinoscopy (n=491), EBUS-TBNA (n=14),
transbronchial biopsy (EBB) (n=102) or EBUS-TBNA+EBBs (n=3) to obtain tissue specimens for
pathological diagnosis.
Results: The positive rate of EBUS-TBNA+EBB and Mediastinoscopy was 100% which was significant
higher than that of EBUS-TBNA and EBB with statistical difference (p<0.05). The medical expenses
during the hospitalization were significantly different among the groups (p<0.05). The average
hospitalization costs for mediastinoscopy were significantly higher than those for endoscopy such as
EBUS-TBNA (p<0.005). And more than 13 punctures didn’t improve the positive rate of diagnosis, but
may increase the risk of bleeding.
Conclusion: EBUS-TBNA is a safe and accurate biopsy technique. The diagnostic positive rate is similar
to the mediastinoscopy with less postoperative complications, and medical costs.

Author(s): Hui Mai, Yongxiango Zhango, Wei Jias, Yuechuan Li

Abstract Full Text PDF