Biomedical Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +1-504-608-2390

Research Article - Biomedical Research (2018) Volume 29, Issue 14

Comparative study of different phytomolecules acting on hRBC to treat rheumatoid arthritis

Rheumatoid arthritis is a chronic inflammatory disease condition in synovial joints causing progressive destruction of synovial fluid resulting moderate to severe pain. Oxidative stress plays a major role in inflammation. Free radicals which are found to have in our body, either as a product of metabolism or incorporated from our environment, plays a major role in formation of oxidative stress, that leads to inflammation. To reduce this oxidative stress anti-oxidant may contribute in management of inflammation. In this study, the antioxidant and anti-inflammatory property of tartaric acid and β- carotene has established and compared with vitamin C and diclofenac sodium as standard drug. The free radical scavenging assay and protein denaturation assay was conducted for this purpose. The % inhibition confirmed the activity of individual molecules. According to the study outcome, Tartaric Acid is more effective antioxidant and anti-inflammatory agent than β-carotene. And so far it can be used as anti-rheumatoid arthritic agent. The IC50 values and graphical representations confirm the result.

Author(s): Sourav Das, Bala A, Mohi Iqbal Mohammed Abdul, Sabahuddin Siddique, Syed Ata Ur Rahman, Samah Ali, Durdana Lateef, Shubhasis Dan, Anirbandeep Bose

Abstract Full Text PDF

Get the App

best replica reviews