Research Article - Journal of Pharmacology and Therapeutic Research (2018) Volume 2, Issue 3
Assessment of amino acid in hypertensive patients.
Introduction: Hypertension is a global disease and in 95% of cases the cause is unidentified. Its early diagnosis and management can block severe complications such as ischemic heart disease (IHD). Moreover the combination of lipids with IHD is important fact. Despite that abnormally high levels of amino acid (homocysteine) were detect to be strongly connected to a raise hazard of coronary artery disease.
Objectives: To assess plasma homocysteine strengths level in patients having hypertension was on treatment.
Methods: Plasma homocysteine strengthens were calculated using High Presentation Liquid Chromatography (HPLC) with Ultraviolet finder in 60 hypertensive patients samples (27 male and 33 female) aged 35 years and more. VLDL-cholesterol, LDL-cholesterol, HDL-cholesterol, Cholesterol and triglyceride were resolved. The frequency of high total homocysteine rates were resolved by contrast with usual indications.
Results: Plasma homocysteine grade were greatly higher in sick than in typical population. Serum cholesterol and triglyceride strengths were also greatly above in patients than in typical population with no link to the grade of homocysteine which is considered as a certain detached heart risk factor.
Conclusions: The study concludes that plasma homocysteine grades were noticeably uppermost in patients than in control groups. No significant variation observed among male and female patients.Author(s): Younis Khider