Research Article - Journal of Biochemistry and Biotechnology (2022) Volume 5, Issue 4
Anticarcinogenic, antimicrobial and broad-spectrum analysis of aqueous leaf extract of Citrullu colocynthis in vitro.
Breast cancer is the leading cause of death among women around the world. Systemic toxicity, metastasis, tumor recurrence, off-target effects, and drug resistance are all severe drawbacks of current treatments. Due to the excellent anticancer potential at very low concentrations, phytochemicals such as secondary metabolites have received interest in recent years. Citrullus colocynthis is a well-known medicinal herb. Therapeutic phytochemicals abound in its leaves, fruits, and roots. saponins, phenols, tannins, flavones, flavonoids, alkaloids, glycosides, and terpenoids are among them. The plant extract proves to have promising anticancer potential by inhibiting the MCF-7 breast cancer cell line. The spectrum analysis of the aqueous leaf extract of Citrullus colocynthis showed the presence of many compounds which are responsible for the anticarcinogenic activity.
Author(s): Lakshmanan1 , Rohini A2 *, Fathima Sumaya1 , P Usha3